Speaker Search Results

Scientific Session

Auditorium

26.5.2026

09:30 – 10:45h

Mechanistic Roles of Transglutaminase in Cardiovascular and Emerging Pathologies

Chair: Lakshmi Santhanam (US)

Introduction
Lakshmi Santhanam, Johns Hopkins University School of Medicine

09:30h - 10:00h

Scientific Session

Auditorium

26.5.2026

09:30 – 10:45h

Mechanistic Roles of Transglutaminase in Cardiovascular and Emerging Pathologies

Chair: Lakshmi Santhanam (US)

Factor XIII-A and plasma fibronectin in liver-bone crosstalk.
Mari T. Kaartinen, McGill University, Canada

10:00h - 10:30h

Scientific Session

Auditorium

26.5.2026

09:30 – 10:45h

Mechanistic Roles of Transglutaminase in Cardiovascular and Emerging Pathologies

Chair: Lakshmi Santhanam (US)

Short Talk - Spatially resolved TGM2 in Immunoglobulin A Nephropathy (IgAN) disease progression
Suraj Lama, Nottingham Trent University, UK

10:30h - 10:45h

Keynote Lecture

Auditorium

25.5.2026

16:30 – 18:00h

Opening Session

Chair: Luigi Leanza (IT)

Opening Lecture - Type 2 transglutaminase: the epigenetic face of a cytoplasmic enzyme.
Mauro Piacentini, University of Rome Tor Vergata, Italy

16:30h - 17:15h

Keynote Lecture

Auditorium

25.5.2026

16:30 – 18:00h

Opening Session

Chair: Luigi Leanza (IT)

Keynote Lecture 1 - Protein monoaminylation: novel mechanisms of neural development, plasticity, and disease
Ian Maze, Icahn School of Medicine at Mount Sinai, USA - (IUBMB supported Lecture)

17:15h - 18:00h

Scientific Session

Auditorium

26.5.2026

11:30 – 12:45h

Flash talks and Plant Transglutaminase

Chairs: Lakshmi Santhanam (US) TBD

Flash Talk - TG2 modulation to improve sexual health: Effects on vascular function and fibrosis in high glucose conditions
Elif Alan Albayrak, Aarhus University, Denmark

11:30h - 11:34h

Scientific Session

Auditorium

26.5.2026

11:30 – 12:45h

Flash talks and Plant Transglutaminase

Chairs: Lakshmi Santhanam (US) TBD

Flash Talk - Bionformatics and functional genomics analysis of nuclear Transglutaminase 2 (TG2) in all-trans retinoic acid (ATRA) differentiated NB4 cells
Wedean Al-Hadban, University of Debrecen, Hungary

11:34h - 11:38h

Scientific Session

Auditorium

26.5.2026

11:30 – 12:45h

Flash talks and Plant Transglutaminase

Chairs: Lakshmi Santhanam (US) TBD

Flash Talk - Transglutaminase II gene silencing identifies RUNX1T1 as a new target in glioblastoma
Rossella Di Paola, University of Campania “Vanvitelli”, Italy

11:38h - 11:42h

Scientific Session

Auditorium

26.5.2026

11:30 – 12:45h

Flash talks and Plant Transglutaminase

Chairs: Lakshmi Santhanam (US) TBD

Flash Talk - Studying of transglutaminase 2 (TG2) oligomerization
Daniil Sidorov, Ajinomoto Genetika Research Institute (AGRI) Moscow, Russia

11:42h - 11:46h

Scientific Session

Auditorium

26.5.2026

14:30 – 15:45h

Transglutaminase in Cancer: Mechanisms and Clinical Implications

Chair: Nicoletta Bianchi (IT)

Introduction
Nicoletta Bianchi, University of Ferrara, Italy

14:30h - 15:00h

Scientific Session

Auditorium

26.5.2026

14:30 – 15:45h

Transglutaminase in Cancer: Mechanisms and Clinical Implications

Chair: Nicoletta Bianchi (IT)

Invited Talk - Transglutaminase 2 (TG2) exacerbates ovarian cancer survival by directly inactivating GSK3β: Is TG2 a primordial chaperone for tumor suppressors?
Soo-Youl Kim, National Cancer Centre, Korea

15:00h - 15:30h

Scientific Session

Auditorium

26.5.2026

14:30 – 15:45h

Transglutaminase in Cancer: Mechanisms and Clinical Implications

Chair: Nicoletta Bianchi (IT)

Short Talk - Transglutaminase Type 2 orchestrates mitochondrial and lipid metabolism to boost triple negative breast cancer progression
Alessia Ruzza, University of Padova, Italy

15:30h - 15:45h

Scientific Session

Auditorium

26.5.2026

15:45 – 16:45h

FEBS Session

Chairs: Luigi Leanza (IT) Elisabetta Verderio Edwards (UK)

TBA
Ian Riemer, FEBS Member in Charge

15:45h - 16:15h

Scientific Session

Auditorium

26.5.2026

15:45 – 16:45h

FEBS Session

Chairs: Luigi Leanza (IT) Elisabetta Verderio Edwards (UK)

FEBS Press: not-for-profit publishing
Michela Notarangelo, Molecular Oncology Editor

16:15h - 16:45h

Scientific Session

Auditorium

27.5.2026

09:30 – 10:55h

Transglutaminase Pathways in Neurodegeneration and Neurological Disorders 1

Chair: Gail V. W. Johnson (US)

Introduction
Gail V W Johnson, University of Rochester, USA

09:30h - 10:00h

Scientific Session

Auditorium

27.5.2026

09:30 – 10:55h

Transglutaminase Pathways in Neurodegeneration and Neurological Disorders 1

Chair: Gail V. W. Johnson (US)

Invited Talk - Expanding the histone monoaminylation landscape mediated by Transglutaminases
David Vinson, Icahn School of Medicine Mount Sinai, USA

10:00h - 10:30h

Scientific Session

Auditorium

27.5.2026

09:30 – 10:55h

Transglutaminase Pathways in Neurodegeneration and Neurological Disorders 1

Chair: Gail V. W. Johnson (US)

Long Talk - Imaging mass cytometry identifies TG2 as a driver of spatial stress-state remodeling after spinal cord injury
Damien Pearse, University of Miami “Miller School of Medicine”, USA

10:30h - 10:55h

Scientific Session

Auditorium

27.5.2026

11:45 – 12:45h

Transglutaminase Pathways in Neurodegeneration and Neurological Disorders 2

Chair: Gail V. W. Johnson (US)

Invited Talk - Tissue Transglutaminase in Multiple Sclerosis
Anne Marie Van Dam, VU Univ Medical Center Amsterdam, The Netherlands

11:45h - 12:15h

Scientific Session

Auditorium

27.5.2026

11:45 – 12:45h

Transglutaminase Pathways in Neurodegeneration and Neurological Disorders 2

Chair: Gail V. W. Johnson (US)

Short Talk - Exploring the nucleic acid binding ability of human neuronal transglutaminase 6
Alaa Rahim, University of Debrecen, Hungary

12:15h - 12:30h

Scientific Session

Auditorium

27.5.2026

11:45 – 12:45h

Transglutaminase Pathways in Neurodegeneration and Neurological Disorders 2

Chair: Gail V. W. Johnson (US)

Short Talk - Transglutaminase 2 as a novel therapeutic target to study ER-mitochondria contact sites in Alzheimer disease using iPSC model
Fiorella Colasuonno, University of Rome “Tor Vergata”, Italy

12:30h - 12:45h

Young Scientists Training

Auditorium

27.5.2026

14:30 – 15:30h

Young scientists training session

Chair: Karoly Jambrovics (HU)

How to prepare a scientific talk
Federica Rossin, University of Rome “Tor Vergata”, Italy

14:30h - 14:50h

Young Scientists Training

Auditorium

27.5.2026

14:30 – 15:30h

Young scientists training session

Chair: Karoly Jambrovics (HU)

How to prepare a fellowship application
Martina Gabrielli, Nottingham Trent University, UK

14:50h - 15:10h

Young Scientists Training

Auditorium

27.5.2026

14:30 – 15:30h

Young scientists training session

Chair: Karoly Jambrovics (HU)

Academia vs Industry: the perspective for the scientists
TBD

15:10h - 15:30h

Scientific Session

Auditorium

27.5.2026

15:30 – 16:45h

Signaling Pathways: How Transglutaminase Shapes Cell Fate 1

Chairs: Kiyotaka Hitomi (JP) TBD

Introduction
Kiyotaka Hitomi, Nagoya University, Japan

15:30h - 16:00h

Scientific Session

Auditorium

27.5.2026

15:30 – 16:45h

Signaling Pathways: How Transglutaminase Shapes Cell Fate 1

Chairs: Kiyotaka Hitomi (JP) TBD

Invited Talk - Moonlighting transglutaminases: Revealing RNA-binding ability of family members
Robert Kiraly, University of Debrecen, Hungary

16:00h - 16:30h

Scientific Session

Auditorium

27.5.2026

15:30 – 16:45h

Signaling Pathways: How Transglutaminase Shapes Cell Fate 1

Chairs: Kiyotaka Hitomi (JP) TBD

Short Talk - Transglutaminase activity and plasma fibronectin ECM assembly in preosteoblast cultures are regulated by surface stiffness
Pier Raffaele Zarro, McGill University, Canada

16:30h - 16:45h

Scientific Session

Auditorium

27.5.2026

17:30 – 18:15h

Signaling Pathways: How Transglutaminase Shapes Cell Fate 2

Chairs: Kiyotaka Hitomi (JP) TBD

Invited Talk - Cryo-EM structure of transglutaminase 2 in complex with fibronectin
Julie Elisabeth Heggelund, University of Oslo, Norway

17:30h - 18:00h

Scientific Session

Auditorium

27.5.2026

17:30 – 18:15h

Signaling Pathways: How Transglutaminase Shapes Cell Fate 2

Chairs: Kiyotaka Hitomi (JP) TBD

Short Talk - Cystamine Uncovers a TG2-Dependent Axis Regulating Melanogenesis in Melanoma
Federica Rossin, University of Rome “Tor Vergata”, Italy

18:00h - 18:15h

Scientific Session

Elettra

28.5.2026

09:30 – 10:55h

Transglutaminase-Mediated Regulation of ECM Dynamics and Fibrotic Process 1

Chair: Elisabetta Verderio Edwards (UK)

Introduction
Elisabetta V. Edwards, Nottingham Trent University, UK and University of Bologna IT

09:30h - 10:00h

Scientific Session

Elettra

28.5.2026

09:30 – 10:55h

Transglutaminase-Mediated Regulation of ECM Dynamics and Fibrotic Process 1

Chair: Elisabetta Verderio Edwards (UK)

Invited Talk - The role of transglutaminase in renal fibrosis and diabetes
Timothy Johnson, Mestag Therapeutics, UK

10:00h - 10:30h

Scientific Session

Elettra

28.5.2026

09:30 – 10:55h

Transglutaminase-Mediated Regulation of ECM Dynamics and Fibrotic Process 1

Chair: Elisabetta Verderio Edwards (UK)

Long Talk - Elucidation of pathogenic molecular mechanisms of fibrosis by targeting crosslinking enzymes
Hidechi Tatsukawa, Nagoya University, Japan

10:30h - 10:55h

Scientific Session

Elettra

28.5.2026

11:30 – 12:45h

Transglutaminase-Mediated Regulation of ECM Dynamics and Fibrotic Process 2

Chair: Elisabetta V. Edwards (UK)

Invited Talk - Preclinical Evidence from a Humanized Mouse Model
Fabio Stellari, Experimental Pharmacology & Translational Science Department – CHIESI

11:30h - 11:50h

Scientific Session

Elettra

28.5.2026

11:30 – 12:45h

Transglutaminase-Mediated Regulation of ECM Dynamics and Fibrotic Process 2

Chair: Elisabetta V. Edwards (UK)

Short Talk - A novel pathophysiological mechanism of renal tubular injury mediated by Transglutaminase 1
Y. Fujisawa, Nagoya University, Japan

12:15h - 12:30h

Scientific Session

Elettra

28.5.2026

11:30 – 12:45h

Transglutaminase-Mediated Regulation of ECM Dynamics and Fibrotic Process 2

Chair: Elisabetta V. Edwards (UK)

Short Talk - Extracellular Vesicles as a new platform for investigating extracellular Transglutaminase 2 in idiopathic pulmonary fibrosis
Maria Pia Savoca, Nottingham Trent University, UK

12:30h - 12:45h

Scientific Session

Elettra

28.5.2026

14:15 – 15:45h

Triggering the Immune system: Transglutaminase in Celiac Disease and Inflammation 1

Chair: Ludvig Sollid (NO)

Introduction
Ludvig Sollid, University of Oslo, Norway

14:15h - 14:45h

Scientific Session

Elettra

28.5.2026

14:15 – 15:45h

Triggering the Immune system: Transglutaminase in Celiac Disease and Inflammation 1

Chair: Ludvig Sollid (NO)

Invited Talk - Transglutaminase 2 as a context-dependent signalling hub in inflammation, survival, and cellular stress responses
Károly Jambrovics, University of Debrecen, Hungary

14:45h - 15:15h

Scientific Session

Elettra

28.5.2026

14:15 – 15:45h

Triggering the Immune system: Transglutaminase in Celiac Disease and Inflammation 1

Chair: Ludvig Sollid (NO)

Short Talk - Transglutaminase Type 2 regulates mtDNA transcription, chemoresistance and immune cell recruitment in melanoma
Federica Vianello, University of Padova, Italy

15:15h - 15:30h

Scientific Session

Elettra

28.5.2026

14:15 – 15:45h

Triggering the Immune system: Transglutaminase in Celiac Disease and Inflammation 1

Chair: Ludvig Sollid (NO)

Short Talk - Goblet cell associated antigen passages (GAPs) as an alternative pathway
Christian Recktenwald, University of Gothenburg, Sweden

15:30h - 15:45h

Scientific Session

Elettra

28.5.2026

16:30 – 17:30h

Triggering the Immune system: Transglutaminase in Celiac Disease and Inflammation 2

Chair: Ludvig Sollid (NO)

Invited Talk - The TG2/LRP1 Pathway for Antigen Presentation in Celiac Disease
Chaitan Khosla, Stanford University, USA

16:30h - 17:00h

Scientific Session

Elettra

28.5.2026

16:30 – 17:30h

Triggering the Immune system: Transglutaminase in Celiac Disease and Inflammation 2

Chair: Ludvig Sollid (NO)

Short Talk - TG2 upregulation is associated with proteostatic and mitochondrial stress in progressive Multiple Sclerosis
Mousumi Ghosh, University of Miami “Miller School of Medicine”, USA

17:00h - 17:15h

Scientific Session

Elettra

28.5.2026

16:30 – 17:30h

Triggering the Immune system: Transglutaminase in Celiac Disease and Inflammation 2

Chair: Ludvig Sollid (NO)

Short Talk - Cerebellar Transcriptomic Signatures Implicate Protein Turnover and Mitochondrial Dysfunction in Gluten Ataxia
Mara Luciana Floare, University of Sheffield, UK

17:15h - 17:30h

Scientific Session

Elettra

29.5.2026

09:30 – 11:45h

Tools and Strategies for Modulating Transglutaminase Activity

Chairs: Jeffrey W. Keillor (CA) TBD

Introduction
Jeffrey W Keillor, University of Ottawa, Canada

09:30h - 10:00h

Scientific Session

Elettra

29.5.2026

09:30 – 11:45h

Tools and Strategies for Modulating Transglutaminase Activity

Chairs: Jeffrey W. Keillor (CA) TBD

Invited Talk - Sex-mediated effects of transglutaminase 2 inhibition on endothelial function in human resistance arteries from diabetic and non-diabetic patients
Estefano Pinilla, Aarhus Universitet, Denmark

10:00h - 10:30h

Scientific Session

Elettra

29.5.2026

09:30 – 11:45h

Tools and Strategies for Modulating Transglutaminase Activity

Chairs: Jeffrey W. Keillor (CA) TBD

Short Talk - Exploring Substrate Selectivity in Transglutaminases
Sergei Ivashchenko, Moscow Institute of physics and technology, Russia

10:30h - 10:45h

Scientific Session

Elettra

29.5.2026

09:30 – 11:45h

Tools and Strategies for Modulating Transglutaminase Activity

Chairs: Jeffrey W. Keillor (CA) TBD

Short Talk - Diamino Variants of Piperazine-Based Tissue Transglutaminase Inhibitors
Brianna Ryan, University of Ottawa, Canada

10:45h - 11:00h

Scientific Session

Elettra

29.5.2026

09:30 – 11:45h

Tools and Strategies for Modulating Transglutaminase Activity

Chairs: Jeffrey W. Keillor (CA) TBD

Short Talk - Development of a single EV quantification method for transglutaminase 2-mediated protein crosslinking
Michael Joseph, Nottingham Trent University, United Kingdom

11:00h - 11:15h

Scientific Session

Elettra

28.5.2026

11:30 – 12:45h

Transglutaminase-Mediated Regulation of ECM Dynamics and Fibrotic Process 2

Chair: Elisabetta V. Edwards (UK)

Invited Talk - Pharmacological Evaluation in Diseased Human Lung Fibroblasts and Ex Vivo Lung Tissue Models
Gessica Marchini, Experimental Pharmacology & Translational Science Department – CHIESI

11:50h - 12:15h

Scientific Session

Auditorium

26.5.2026

11:30 – 12:45h

Flash talks and Plant Transglutaminase

Chairs: Lakshmi Santhanam (US) TBD

Flash Talk - Targeting transglutaminase 2 in idiopathic pulmonary fibrosis: insights from 2D cell cultures and advanced 3D lung models
Beatrice Spagnoli, University of Parma, Italy

11:46h - 11:50h

Scientific Session

Auditorium

26.5.2026

11:30 – 12:45h

Flash talks and Plant Transglutaminase

Chairs: Lakshmi Santhanam (US) TBD

Flash Talk - Amino Acid Residue and Hydrophobic Group Substitutions in Covalent Inhibitors of Transglutaminase
Sarah Tribe, University of Ottawa, Canada

11:50h - 11:54h

Scientific Session

Auditorium

26.5.2026

11:30 – 12:45h

Flash talks and Plant Transglutaminase

Chairs: Lakshmi Santhanam (US) TBD

Flash Talk - Unravelling the impact of TG2 modulation in endothelial cells
Elisabetta Zaltron, University of Padova, Italy

11:54h - 12:00h

Scientific Session

Auditorium

26.5.2026

11:30 – 12:45h

Flash talks and Plant Transglutaminase

Chairs: Lakshmi Santhanam (US) TBD

Invited Talk - The Green Transglutaminase Puzzle
Stefano Del Duca, University of Bologna, Italy

12:00h - 12:30h

Keynote Lecture

Auditorium

26.5.2026

18:30 – 19:15h

Keynote Session

Towards a therapeutic solution with tissue transglutaminase degraders
Daniela Matei, Northwestern University, USA

18:30h - 19:15h

Scientific Session

Elettra

29.5.2026

09:30 – 11:45h

Tools and Strategies for Modulating Transglutaminase Activity

Chairs: Jeffrey W. Keillor (CA) TBD

Short Talk - Transglutaminase 2-Associated Signature in Mesenchymal Circulating Tumor Cells: Insights from Single-Cell Analysis
Anna Terrazzan, University of Ferrara, Italy

11:15h - 11:30h

Chairs' welcome/conclusions

Elettra

29.5.2026

12:15 – 13:00h

Closing Session

Chairs: Luigi Leanza (IT) Elisabetta V. Edwards (UK)

Concluding Remarks, Evaluation, Awards and Future conferences Discussion
Kiyotaka Hitomi, Nagoya University, Japan

12:15h - 12:45h

Chairs' welcome/conclusions

Elettra

29.5.2026

12:15 – 13:00h

Closing Session

Chairs: Luigi Leanza (IT) Elisabetta V. Edwards (UK)

Wrap-up and Departure
Luigi Leanza, University of Padova, Italy - Elisabetta Verderio Edwards, Nottingham Trent University, UK - University of Bologna, IT

12:45h - 13:00h